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Specifying the molecular pattern of sporadic parathyroid tumorigenesis—The Y282D variant of the GCM2 gene

Objective: Sporadic carcinoma of the parathyroid glands is a rare malignant neoplasia. The GCM2 gene encodes a transcription factor that is crucial to embryonic parathyroid development. The Y282D variant of GCM2 exhibits increased transcriptional activity, and the presence of this variant is signifi...

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Foilsithe in:Biomed Pharmacother
Main Authors: Marchiori, Elena, Pelizzo, Maria Rosa, Herten, Monika, Townsend, Danyelle M., Rubello, Domenico, Boschin, Isabella Merante
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361162/
https://ncbi.nlm.nih.gov/pubmed/28609842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2017.05.028
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