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Complex structural rearrangements are present in high-grade dysplastic Barrett’s oesophagus samples

BACKGROUND: Oesophageal adenocarcinoma (EAC) incidence is increasing and has a poor survival rate. Barrett’s oesophagus (BE) is a precursor condition that is associated with EAC and often occurs in conjunction with chronic gastro-oesophageal reflux, however many individuals diagnosed with BE never p...

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Bibliographic Details
Published in:BMC Med Genomics
Main Authors: Newell, Felicity, Patel, Kalpana, Gartside, Michael, Krause, Lutz, Brosda, Sandra, Aoude, Lauren G., Loffler, Kelly A., Bonazzi, Vanessa F., Patch, Ann-Marie, Kazakoff, Stephen H., Holmes, Oliver, Xu, Qinying, Wood, Scott, Leonard, Conrad, Lampe, Guy, Lord, Reginald V., Whiteman, David C., Pearson, John V., Nones, Katia, Waddell, Nicola, Barbour, Andrew P.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360790/
https://ncbi.nlm.nih.gov/pubmed/30717762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0476-9
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