Calcium channel blockade with nimodipine reverses MRI evidence of cerebral oedema following acute hypoxia

Acute cerebral hypoxia causes rapid calcium shifts leading to neuronal damage and death. Calcium channel antagonists improve outcomes in some clinical conditions, but mechanisms remain unclear. In 18 healthy participants we: (i) quantified with multiparametric MRI the effect of hypoxia on the thalam...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Rowland, Matthew J, Ezra, Martyn, Winkler, Anderson, Garry, Payashi, Lamb, Catherine, Kelly, Michael, Okell, Thomas W, Westbrook, Jon, Wise, Richard G, Douaud, Gwenaëlle, Pattinson, Kyle TS
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360646/
https://ncbi.nlm.nih.gov/pubmed/28857714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17726624
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