Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration

Recent fate-mapping studies in mice have provided substantial evidence that mature adult hepatocytes are a major source of new hepatocytes after liver injury. In other systems, integrin αvβ8 has a major role in activating transforming growth factor (TGF)-β, a potent inhibitor of hepatocyte prolifera...

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Pubblicato in:Am J Pathol
Autori principali: Greenhalgh, Stephen N., Matchett, Kylie P., Taylor, Richard S., Huang, Katherine, Li, John T., Saeteurn, Koy, Donnelly, Mhairi C., Simpson, Eilidh E.M., Pollack, Joshua L., Atakilit, Amha, Simpson, Kenneth J., Maher, Jacquelyn J., Iredale, John P., Sheppard, Dean, Henderson, Neil C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360354/
https://ncbi.nlm.nih.gov/pubmed/30448409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.10.007
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