Identification of Putative UL54 (ICP27) Transcription Regulatory Sequences Binding to Oct-1, v-Myb, Pax-6 and Hairy in Herpes Simplex Viruses

An oncolytic herpes simplex virus (oHSV) has proven amenable in oncolytic virotherapy and was approved to treat melanoma. The immediate-early (IE) protein ICP27 encoded by gene UL54 is essential for HSV infection. Post-transcriptional modification of UL54 would increase tumor targeting of oHSVs. How...

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Publicado en:J Cancer
Main Authors: Wang, Ying-Ying, Lyu, Yan-Ning, Xin, Hong-Yi, Cheng, Jun-Ting, Liu, Xiao-Qin, Wang, Xian-Wang, Peng, Xiao-Chun, Xiang, Ying, Xin, Victoria W., Lu, Cheng-Biao, Ren, Bo-Xu, Liang, Yan-Fang, Ji, Jia-Fu, Ma, Zhaowu, Cui, Shu-Zhong, Xin, Hong-Wu
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360293/
https://ncbi.nlm.nih.gov/pubmed/30719137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.29787
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