IL-27 Promotes Human Placenta–Derived Mesenchymal Stromal Cell Ability To Induce the Generation of CD4(+)IL-10(+)IFN-γ(+) T Cells via the JAK/STAT Pathway in the Treatment of Experimental Graft-versus-Host Disease

Human mesenchymal stromal cells (MSCs) harbor immunomodulatory properties to induce the generation of suppressive T cells. MSCs have been successfully used in treating graft-versus-host disease (GVHD) accompanied by abundant inflammatory cytokines such as IL-27. This study investigated the effects o...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yi, Junzhu, Chen, Zhenghua, Xu, Fenghuang, Wang, ZhuoYa, Zhang, Aiping, Liu, Tongshen, Zhao, Nannan, Xiong, Yanlian, Jiang, Guosheng, Ma, Junjie, Luan, Xiying
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2019
Assuntos:
Immune Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360257/
https://ncbi.nlm.nih.gov/pubmed/30651340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800963
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