Drug Loading Augmentation in Polymeric Nanoparticles Using a Coaxial Turbulent Jet Mixer: Yong Investigator Perspective

HYPOTHESIS: In conventional ‘bulk’ nanoprecipitation, the capacity to load hydrophobic drugs into the polymeric nanoparticles (NPs) is limited to about 1%. The size distribution of the resulting NPs becomes polydisperse when higher precursor concentration is used to increase the drug loading. Hence,...

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Detalhes bibliográficos
Publicado no:J Colloid Interface Sci
Main Authors: Lim, Jong-Min, Cai, Truong, Mandaric, Stefan, Chopra, Sunandini, Han, Hyeonwoo, Jang, Seokkyu, Choi, Won Il, Langer, Robert, Farokhzad, Omid C., Karnik, Rohit
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360111/
https://ncbi.nlm.nih.gov/pubmed/30500466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcis.2018.11.029
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