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PD-L1 Inhibition with Avelumab for Metastatic Merkel Cell Carcinoma

INTRODUCTION: Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer that lacks durable responses to traditional chemotherapy. AREAS COVERED: After MCC was shown to be an immunogenic tumor, small trials revealed high objective response rates to PD-1/PD-L1 checkpoint inhibito...

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Detalhes bibliográficos
Publicado no:Expert Rev Clin Pharmacol
Main Authors: Gaiser, Maria Rita, Bongiorno, Michelle, Brownell, Isaac
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360093/
https://ncbi.nlm.nih.gov/pubmed/29478343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17512433.2018.1445966
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