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GSK-3β regulates the endothelial-to-mesenchymal transition via reciprocal crosstalk between NSCLC cells and HUVECs in multicellular tumor spheroid models

BACKGROUND: Chemotherapy used for patients with unresectable lung tumors remains largely palliative due to chemoresistance, which may be due to tumor heterogeneity. Recently, multiple studies on the crosstalk between lung cancer cells and their tumor microenvironment (TME) have been conducted to und...

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Publicado en:J Exp Clin Cancer Res
Main Authors: Kim, Se-Hyuk, Song, Yeonhwa, Seo, Haeng Ran
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359813/
https://ncbi.nlm.nih.gov/pubmed/30709379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1050-1
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