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Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme

BACKGROUND: In recent years, PD-1/PD-L1 immune checkpoint inhibitors have improved cancer therapy in many tumor types, but no benefit of immune checkpoint therapy has been found in glioblastoma multiforme (GBM). Based on the results of our earlier work, which showed a reduction of PD-L1 expression i...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Heynckes, Sabrina, Daka, Karam, Franco, Pamela, Gaebelein, Annette, Frenking, Jan Hendrik, Doria-Medina, Roberto, Mader, Irina, Delev, Daniel, Schnell, Oliver, Heiland, Dieter Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359796/
https://ncbi.nlm.nih.gov/pubmed/30709339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5308-y
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