Overexpressed histone acetyltransferase 1 regulates cancer immunity by increasing programmed death-ligand 1 expression in pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma is one of the leading causes of cancer-related death worldwide. Immune checkpoint blockade therapy, including anti-PD-1 and anti-PD-L1, is a new therapeutic strategy for cancer treatment but the monotherapy with PD-L1 inhibitors for pancreatic cancer is a...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Fan, Ping, Zhao, Jingyuan, Meng, Zibo, Wu, Heyu, Wang, Bo, Wu, Heshui, Jin, Xin
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359760/
https://ncbi.nlm.nih.gov/pubmed/30709380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1044-z
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