Growth-dependent recombinant product formation kinetics can be reproduced through engineering of glucose transport and is prone to phenotypic heterogeneity

BACKGROUND: Escherichia coli W3110 and a group of six isogenic derivatives, each displaying distinct specific rates of glucose consumption were characterized to determine levels of GFP production and population heterogeneity. These strains have single or combinatory deletions in genes encoding phosp...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Microb Cell Fact
Κύριοι συγγραφείς: Fragoso-Jiménez, Juan Carlos, Baert, Jonathan, Nguyen, Thai Minh, Liu, Wenzheng, Sassi, Hosni, Goormaghtigh, Frédéric, Van Melderen, Laurence, Gaytán, Paul, Hernández-Chávez, Georgina, Martinez, Alfredo, Delvigne, Frank, Gosset, Guillermo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2019
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359759/
https://ncbi.nlm.nih.gov/pubmed/30710996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1073-5
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