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Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells

Obstructive sleep apnea (OSA) affects a significant proportion of the population and is linked to increased rates of cancer development and a worse cancer outcome. OSA is characterized by nocturnal intermittent hypoxia and animal models of OSA-like intermittent hypoxia show increased tumor growth an...

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Publicat a:Int J Mol Sci
Autors principals: Martinez, Chloe-Anne, Kerr, Bernadette, Jin, Charley, Cistulli, Peter A., Cook, Kristina M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359625/
https://ncbi.nlm.nih.gov/pubmed/30669593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020445
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