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5-Hydroxymethylfurfural Mitigates Lipopolysaccharide-Stimulated Inflammation via Suppression of MAPK, NF-κB and mTOR Activation in RAW 264.7 Cells

5-Hydroxymethylfurfural (5-HMF) is found in many food products including honey, dried fruits, coffee and black garlic extracts. Here, we investigated the anti-inflammatory activity of 5-HMF and its underlying mechanisms in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. 5-HMF pretreatment rangi...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kong, Fanhui, Lee, Bae Hoon, Wei, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359491/
https://ncbi.nlm.nih.gov/pubmed/30642099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24020275
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