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Dual Role of Triptolide in Interrupting the NLRP3 Inflammasome Pathway to Attenuate Cardiac Fibrosis

In a previous paper, we reported that triptolide (TP), a commonly used immunomodulator, could attenuate cardiac hypertrophy. This present study aimed to further explore the inhibition of cardiac fibrosis by TP and the possible mechanism from the perspective of the NOD-like receptor protein 3 (NLRP3)...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pan, Xi-Chun, Liu, Ya, Cen, Yan-Yan, Xiong, Ya-Lan, Li, Jing-Mei, Ding, Yuan-Yuan, Tong, Yang-Fei, Liu, Tao, Chen, Xiao-Hong, Zhang, Hai-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359320/
https://ncbi.nlm.nih.gov/pubmed/30654511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020360
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