Dual Role of Triptolide in Interrupting the NLRP3 Inflammasome Pathway to Attenuate Cardiac Fibrosis

In a previous paper, we reported that triptolide (TP), a commonly used immunomodulator, could attenuate cardiac hypertrophy. This present study aimed to further explore the inhibition of cardiac fibrosis by TP and the possible mechanism from the perspective of the NOD-like receptor protein 3 (NLRP3)...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Pan, Xi-Chun, Liu, Ya, Cen, Yan-Yan, Xiong, Ya-Lan, Li, Jing-Mei, Ding, Yuan-Yuan, Tong, Yang-Fei, Liu, Tao, Chen, Xiao-Hong, Zhang, Hai-Gang
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359320/
https://ncbi.nlm.nih.gov/pubmed/30654511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020360
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