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High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells

Metformin, the most widely prescribed anti-diabetic drug, is shown to possess anti-cancer potential in treatment of cancers, including breast cancer; decreases breast cancer risk; and improves overall survival. However, reports suggest that higher glucose concentrations may negatively impact the ant...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Varghese, Sharon, Samuel, Samson Mathews, Varghese, Elizabeth, Kubatka, Peter, Büsselberg, Dietrich
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359242/
https://ncbi.nlm.nih.gov/pubmed/30626087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9010016
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