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Complexes of Pro-Apoptotic siRNAs and Carbosilane Dendrimers: Formation and Effect on Cancer Cells

This paper examines the complexation of anti-cancer small interfering RNAs (siRNAs) by cationic carbosilane dendrimers, and the interaction of the formed complexes with HeLa and HL-60 cancer cells. Stepwise formation of the complexes accompanied by the evolution of their properties has been observed...

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Vydáno v:Pharmaceutics
Hlavní autoři: Krasheninina, Olga A., Apartsin, Evgeny K., Fuentes, Elena, Szulc, Aleksandra, Ionov, Maksim, Venyaminova, Alya G., Shcharbin, Dzmitry, de la Mata, F. Javier, Bryszewska, Maria, Gόmez, Rafael
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359069/
https://ncbi.nlm.nih.gov/pubmed/30634643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11010025
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