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Optimization of the Factors Affecting the Absorption of Vardenafil from Oral Disintegrating Tablets: A Clinical Pharmacokinetic Investigation

Because of poor solubility and considerable metabolism, vardenafil (VRD) bioavailability is 15%. To overcome this obstacle, this study aimed to increase the solubility, hasten the onset of action, and mask the unpleasant taste of VRD utilizing β-cyclodextrin (β-CD) and formulation of the inclusion c...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmaceutics
Egile Nagusiak: Al-Gethmy, Hytham A., Fahmy, Usama A., Alhakamy, Nabil A., Ahmed, Osama A. A., El-Say, Khalid M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358952/
https://ncbi.nlm.nih.gov/pubmed/30609647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11010011
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