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Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis

BACKGROUND: Melatonin generated in the gastrointestinal tract has mucosal protective effect with inhibiting gastric acid secretion, while increasing gastrin release, which in turn stimulates the contractility of lower esophageal sphincter. Gastroesophageal reflux disease (GERD) is also known to have...

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Publicado en:Medicine (Baltimore)
Main Authors: Bang, Chang Seok, Yang, Young Joo, Baik, Gwang Ho
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Health 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358381/
https://ncbi.nlm.nih.gov/pubmed/30681611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000014241
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