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Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis

BACKGROUND: Melatonin generated in the gastrointestinal tract has mucosal protective effect with inhibiting gastric acid secretion, while increasing gastrin release, which in turn stimulates the contractility of lower esophageal sphincter. Gastroesophageal reflux disease (GERD) is also known to have...

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Bibliographic Details
Published in:Medicine (Baltimore)
Main Authors: Bang, Chang Seok, Yang, Young Joo, Baik, Gwang Ho
Format: Artigo
Language:Inglês
Published: Wolters Kluwer Health 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358381/
https://ncbi.nlm.nih.gov/pubmed/30681611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000014241
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