A Weighted Genetic Risk Score Predicts Surgical Recurrence Independent of High-Risk Clinical Features in Dupuytren’s Disease

BACKGROUND: Dupuytren’s disease is a very common, highly heritable palmar fibromatosis. In a recent genome-wide association study, 26 single-nucleotide polymorphisms were found to be associated with development of Dupuytren’s disease. The authors generated a weighted genetic risk score based on the...

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Publicado en:Plast Reconstr Surg
Autores principales: Riesmeijer, Sophie A., Manley, Oliver W. G., Ng, Michael, Nolte, Ilja M., Broekstra, Dieuwke C., Werker, Paul M. N., Furniss, Dominic
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Hand/Peripheral Nerve: Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358194/
https://ncbi.nlm.nih.gov/pubmed/30688894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0000000000005208
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