Enzymatic activities of circulating plasma proteasomes in newly diagnosed multiple myeloma patients treated with carfilzomib, lenalidomide and dexamethasone

The proteasome inhibitor carfilzomib is highly effective in the treatment of multiple myeloma. It irreversibly binds the chymotrypsin-like active site in the β5 subunit of the 20S proteasome. Despite impressive response rates when carfilzomib is used in combination with immunomodulatory agents in ne...

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Udgivet i:Leuk Lymphoma
Main Authors: Manasanch, Elisabet E., de Larrea, Carlos Fernández, Zingone, Adriana, Steinberg, Seth M., Kwok, Mary, Tageja, Nishant, Bhutani, Manisha, Kazandjian, Dickran, Roschewski, Mark, Wu, Peter, Carter, George, Zuchlinski, Diamond, Mulquin, Marcia, Lamping, Liz, Costello, Rene, Burton, Deborah, Gil, Lindsay A., Figg, William D., Maric, Irina, Calvo, Katherine R., Yuan, Constance, Stetler-Stevenson, Maryalice, Korde, Neha, Landgren, Ola
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357961/
https://ncbi.nlm.nih.gov/pubmed/27687480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2016.1214953
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