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A Golgi-targeting fluorescent probe for labile Fe(ii) to reveal an abnormal cellular iron distribution induced by dysfunction of VPS35

Iron is involved in numerous physiologically essential processes in our body. However, excessive iron is a pathogenic factor in neurodegenerative diseases, causing aberrant oxidative stress. Divalent metal transporter 1 (DMT1) acts as a primary transporter of Fe(ii) ions. The intracellular delivery...

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Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Hirayama, Tasuku, Inden, Masatoshi, Tsuboi, Hitomi, Niwa, Masato, Uchida, Yasuhiro, Naka, Yuki, Hozumi, Isao, Nagasawa, Hideko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal Society of Chemistry 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357701/
https://ncbi.nlm.nih.gov/pubmed/30809369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04386h
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