Association between polymorphisms in the GRIN1 gene 5′ regulatory region and schizophrenia in a northern Han Chinese population and haplotype effects on protein expression in vitro

BACKGROUND: Schizophrenia is a severe neurodevelopmental disorder with a complex genetic and environmental etiology. Abnormal glutamate ionotropic N-methyl-D-aspartate receptor (NMDA) type subunit 1 (NR1) may be a potential cause of schizophrenia. METHODS: We conducted a case-control study to invest...

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Vydáno v:BMC Med Genet
Hlavní autoři: Liu, Yong-ping, Ding, Mei, Zhang, Xi-cen, Liu, Yi, Xuan, Jin-feng, Xing, Jia-xin, Xia, Xi, Yao, Jun, Wang, Bao-jie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357472/
https://ncbi.nlm.nih.gov/pubmed/30704411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-019-0757-3
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