Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis

BACKGROUND: Deregulated c-Abl activity has been intensively studied in a variety of solid tumors and leukemia. The class-I carcinogen Helicobacter pylori (Hp) activates the non-receptor tyrosine kinase c-Abl to phosphorylate the oncoprotein cytotoxin-associated gene A (CagA). The role of c-Abl in Ca...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Posselt, Gernot, Wiesauer, Maria, Chichirau, Bianca E., Engler, Daniela, Krisch, Linda M., Gadermaier, Gabriele, Briza, Peter, Schneider, Sabine, Boccellato, Francesco, Meyer, Thomas F., Hauser-Kronberger, Cornelia, Neureiter, Daniel, Müller, Anne, Wessler, Silja
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357398/
https://ncbi.nlm.nih.gov/pubmed/30704478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0323-9
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