Upregulation of miR-107 expression following hyperbaric oxygen treatment suppresses HMGB1/RAGE signaling in degenerated human nucleus pulposus cells

BACKGROUND: The expression of both high-mobility group box 1 (HMGB1) and receptor for advanced glycation end-products (RAGE) is upregulated in degenerated discs. HMGB1 is known to function as a coupling factor between hypoxia and inflammation in arthritis, and this inflammatory response is modulated...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Niu, Chi-Chien, Lin, Song-Shu, Yuan, Li-Jen, Lu, Meng-Ling, Ueng, Steve W. N., Yang, Chuen-Yung, Tsai, Tsung-Ting, Lai, Po-Liang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357369/
https://ncbi.nlm.nih.gov/pubmed/30704538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1830-1
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