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Predicting drug response of tumors from integrated genomic profiles by deep neural networks

BACKGROUND: The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent study screened for the response of a thousand human cancer cell lines to a wide collection of anti-cancer dru...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Chiu, Yu-Chiao, Chen, Hung-I Harry, Zhang, Tinghe, Zhang, Songyao, Gorthi, Aparna, Wang, Li-Ju, Huang, Yufei, Chen, Yidong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357352/
https://ncbi.nlm.nih.gov/pubmed/30704458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0460-9
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