A graph-based algorithm for estimating clonal haplotypes of tumor sample from sequencing data

BACKGROUND: Haplotype phasing is an important step in many bioinformatics workflows. In cancer genomics, it is suggested that reconstructing the clonal haplotypes of a tumor sample could facilitate a comprehensive understanding of its clonal architecture and further provide valuable reference in cli...

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Dettagli Bibliografici
Pubblicato in:BMC Med Genomics
Autori principali: Wang, Yixuan, Zhang, Xuanping, Ding, Shuai, Geng, Yu, Liu, Jianye, Zhao, Zhongmeng, Zhang, Rong, Xiao, Xiao, Wang, Jiayin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357344/
https://ncbi.nlm.nih.gov/pubmed/30704456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0457-4
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