Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension

Intermedin/adrenomedullin-2 (IMD/AM2), a member of the calcitonin gene-related peptide/AM family, plays an important role in protecting the cardiovascular system. However, its role in the enhanced sympathoexcitation in obesity-related hypertension is unknown. In this study, we investigated the effec...

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Veröffentlicht in:Neurosci Bull
Hauptverfasser: Sun, Jing, Ren, Xing-Sheng, Kang, Ying, Dai, Hang-Bing, Ding, Lei, Tong, Ning, Zhu, Guo-Qing, Zhou, Ye-Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357274/
https://ncbi.nlm.nih.gov/pubmed/30276527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-018-0292-9
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