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Safety Study of Single-Dose Intravenously Administered DOTA-Siglec-9 Peptide in Sprague Dawley Rats

The peptide-based radioactive compound [(68)Ga]Ga-DOTA-Siglec-9 is a novel agent for imaging of inflammation with positron emission tomography. The drug target of [(68)Ga]Ga-DOTA-Siglec-9 is vascular adhesion protein 1. Previous studies have obtained promising results with [(68)Ga]Ga-DOTA-Siglec-9 i...

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Bibliografiske detaljer
Udgivet i:Int J Toxicol
Main Authors: Chrusciel, Paulina, Yatkin, Emrah, Li, Xiang-Guo, Jaakkola, Ulla-Marjut, Knuuti, Juhani, Jalkanen, Sirpa, Roivainen, Anne
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357174/
https://ncbi.nlm.nih.gov/pubmed/30663453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1091581818821606
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