A novel CD7 chimeric antigen receptor-modified NK-92MI cell line targeting T-cell acute lymphoblastic leukemia

Chimeric antigen receptor (CAR) immunotherapy has recently shown promise in clinical trials for B-cell malignancies; however, designing CARs for T-cell based diseases remain a challenge since most target antigens are shared between normal and malignant cells, leading to CAR-T cell fratricide. CD7 is...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: You, Fengtao, Wang, Yinyan, Jiang, Licui, Zhu, Xuejun, Chen, Dan, Yuan, Lei, An, Gangli, Meng, Huimin, Yang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356925/
https://ncbi.nlm.nih.gov/pubmed/30755812
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