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Endolysosomal Ca(2+) Signalling and Cancer Hallmarks: Two-Pore Channels on the Move, TRPML1 Lags Behind!

The acidic vesicles of the endolysosomal (EL) system are emerging as an intracellular Ca(2+) store implicated in the regulation of multiple cellular functions. The EL Ca(2+) store releases Ca(2+) through a variety of Ca(2+)-permeable channels, including Transient Receptor Potential (TRP) Mucolipin 1...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Faris, Pawan, Shekha, Mudhir, Montagna, Daniela, Guerra, Germano, Moccia, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356888/
https://ncbi.nlm.nih.gov/pubmed/30591696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010027
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