Molecular Networking Reveals Two Distinct Chemotypes in Pyrroloiminoquinone-Producing Tsitsikamma favus Sponges

The temperate marine sponge, Tsitsikamma favus, produces pyrroloiminoquinone alkaloids with potential as anticancer drug leads. We profiled the secondary metabolite reservoir of T. favus sponges using HR-ESI-LC-MS/MS-based molecular networking analysis followed by preparative purification efforts to...

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Publicado en:Mar Drugs
Autores principales: Kalinski, Jarmo-Charles J., Waterworth, Samantha C., Siwe Noundou, Xavier, Jiwaji, Meesbah, Parker-Nance, Shirley, Krause, Rui W. M., McPhail, Kerry L., Dorrington, Rosemary A.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356464/
https://ncbi.nlm.nih.gov/pubmed/30654589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17010060
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