Carnosine Prevents Aβ-Induced Oxidative Stress and Inflammation in Microglial Cells: A Key Role of TGF-β1

Carnosine (β-alanyl-L-histidine), a dipeptide, is an endogenous antioxidant widely distributed in excitable tissues like muscles and the brain. Carnosine is involved in cellular defense mechanisms against oxidative stress, including the inhibition of amyloid-beta (Aβ) aggregation and the scavenging...

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Veröffentlicht in:Cells
Hauptverfasser: Caruso, Giuseppe, Fresta, Claudia G., Musso, Nicolò, Giambirtone, Mariaconcetta, Grasso, Margherita, Spampinato, Simona F., Merlo, Sara, Drago, Filippo, Lazzarino, Giuseppe, Sortino, Maria A., Lunte, Susan M., Caraci, Filippo
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356400/
https://ncbi.nlm.nih.gov/pubmed/30658430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010064
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