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Mifepristone Overcomes Tumor Resistance to Temozolomide Associated with DNA Damage Repair and Apoptosis in an Orthotopic Model of Glioblastoma

The standard treatment for glioblastoma multiforme (GBM) is surgery followed by chemo/radiotherapy. A major limitation on patient improvement is the high resistance of tumors to drug treatment, likely responsible for their subsequent recurrence and rapid progression. Therefore, alternatives to the s...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Llaguno-Munive, Monserrat, Romero-Piña, Mario, Serrano-Bello, Janeth, Medina, Luis A., Uribe-Uribe, Norma, Salazar, Ana Maria, Rodríguez-Dorantes, Mauricio, Garcia-Lopez, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356343/
https://ncbi.nlm.nih.gov/pubmed/30583528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010016
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