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TALEN-Mediated Gene Targeting for Cystic Fibrosis-Gene Therapy

Cystic fibrosis (CF) is an inherited monogenic disorder, amenable to gene-based therapies. Because CF lung disease is currently the major cause of mortality and morbidity, and the lung airway is readily accessible to gene delivery, the major CF gene therapy effort at present is directed to the lung....

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Principais autores: Xia, Emily, Zhang, Yiqian, Cao, Huibi, Li, Jun, Duan, Rongqi, Hu, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356284/
https://ncbi.nlm.nih.gov/pubmed/30641980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10010039
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