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NUP214 in Leukemia: It’s More than Transport
NUP214 is a component of the nuclear pore complex (NPC) with a key role in protein and mRNA nuclear export. Chromosomal translocations involving the NUP214 locus are recurrent in acute leukemia and frequently fuse the C-terminal region of NUP214 with SET and DEK, two chromatin remodeling proteins wi...
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| 發表在: | Cells |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356203/ https://ncbi.nlm.nih.gov/pubmed/30669574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010076 |
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