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Functional Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in Dictyostelium discoideum

Autophagy is a highly conserved intracellular degradative pathway that is crucial for cellular homeostasis. During autophagy, the core autophagy protein ATG12 plays, together with ATG5 and ATG16, an essential role in the expansion of the autophagosomal membrane. In this study we analyzed gene replac...

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Bibliographic Details
Published in:Cells
Main Authors: Fischer, Sarah, Rijal, Ramesh, Frommolt, Peter, Wagle, Prerana, Konertz, Roman, Faix, Jan, Meßling, Susanne, Eichinger, Ludwig
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356199/
https://ncbi.nlm.nih.gov/pubmed/30669443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010072
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