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PTMiner: Localization and Quality Control of Protein Modifications Detected in an Open Search and Its Application to Comprehensive Post-translational Modification Characterization in Human Proteome

The open (mass tolerant) search of tandem mass spectra of peptides shows great potential in the comprehensive detection of post-translational modifications (PTMs) in shotgun proteomics. However, this search strategy has not been widely used by the community, and one bottleneck of it is the lack of a...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: An, Zhiwu, Zhai, Linhui, Ying, Wantao, Qian, Xiaohong, Gong, Fuzhou, Tan, Minjia, Fu, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356076/
https://ncbi.nlm.nih.gov/pubmed/30420486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000812
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