A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity

Both protein quality and mitochondrial quality are vital for the cellular activity, and impaired proteostasis and mitochondrial dysfunction are common etiologies of aging and age‐related disorders. Here, we report that the mitochondrial outer membrane protein FUNDC1 interacts with the chaperone HSC7...

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Vydáno v:EMBO J
Hlavní autoři: Li, Yanjun, Xue, Yanhong, Xu, Xiaojun, Wang, Guopeng, Liu, Yiqun, Wu, Hao, Li, Wenhui, Wang, Yueying, Chen, Ziheng, Zhang, Weilin, Zhu, Yushan, Ji, Wei, Xu, Tao, Liu, Lei, Chen, Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356068/
https://ncbi.nlm.nih.gov/pubmed/30591555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798786
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