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Avidity‐driven polarity establishment via multivalent lipid–GTPase module interactions
While Rho GTPases are indispensible regulators of cellular polarity, the mechanisms underlying their anisotropic activation at membranes have been elusive. Using the budding yeast Cdc42 GTPase module, which includes a guanine nucleotide exchange factor (GEF) Cdc24 and the scaffold Bem1, we find that...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356062/ https://ncbi.nlm.nih.gov/pubmed/30559330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899652 |
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