Fractional laser ablation for the targeted cutaneous delivery of an anti-CD29 monoclonal antibody – OS2966

Monoclonal antibodies targeting cytokines are administered parenterally for the systemic treatment of severe psoriasis. However, systemic exposure to the biologic increases the risk of side-effects including immunosuppression, whereas only a small fraction of the active molecules actually reaches th...

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Udgivet i:Sci Rep
Main Authors: Lapteva, Maria, del Río-Sancho, Sergio, Wu, Eric, Carbonell, W. Shawn, Böhler, Christof, Kalia, Yogeshvar N.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355906/
https://ncbi.nlm.nih.gov/pubmed/30705293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36966-0
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