Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier

More than 40% of HIV infections occur via female reproductive tract (FRT) through heterosexual transmission. Epithelial cells that line the female genital mucosa are the first line of defense against HIV-1 and other sexually transmitted pathogens. These sentient cells recognize and respond to extern...

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Vydáno v:Cell Mol Immunol
Hlavní autoři: Nazli, Aisha, Dizzell, Sara, Zahoor, Muhammad Atif, Ferreira, Victor H, Kafka, Jessica, Woods, Matthew William, Ouellet, Michel, Ashkar, Ali A, Tremblay, Michel J, Bowdish, Dawn ME, Kaushic, Charu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355787/
https://ncbi.nlm.nih.gov/pubmed/29553138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.168
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