Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence

BACKGROUND: Cellular senescence is a stable cell-cycle arrest induced by telomere shortening and various types of cellular stress including oxidative stress, oncogene activation, DNA damage etc. Heme oxygenase-1 (HO-1) is an inducible stress-response protein that plays antioxidant and anti-apoptotic...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Shan, Huitong, Li, Tianyu, Zhang, Lijia, Yang, Rui, Li, Yue, Zhang, Mingyu, Dong, Yuechao, Zhou, Yuhong, Xu, Chaoqian, Yang, Baofeng, Liang, Haihai, Gao, Xu, Shan, Hongli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355645/
https://ncbi.nlm.nih.gov/pubmed/30527623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.056
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