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The K(V)7 channel activator retigabine suppresses mouse urinary bladder afferent nerve activity without affecting detrusor smooth muscle K(+) channel currents
KEY POINTS: K(V)7 channels are a family of voltage‐dependent K(+) channels expressed in many cell types, which open in response to membrane depolarization to regulate cell excitability. Drugs that target K(V)7 channels are used clinically to treat epilepsy. Interestingly, these drugs also cause urin...
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| Publicado no: | J Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355639/ https://ncbi.nlm.nih.gov/pubmed/30536555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277021 |
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