ERG6 and ERG2 Are Major Targets Conferring Reduced Susceptibility to Amphotericin B in Clinical Candida glabrata Isolates in Kuwait

Candida glabrata is intrinsically less susceptible to azoles, and resistance to echinocandins and reduced susceptibility (RS) to amphotericin B (AMB) have also been detected. The molecular mechanisms of RS to AMB were investigated in C. glabrata strains in Kuwait by sequence analyses of genes involv...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ahmad, Suhail, Joseph, Leena, Parker, Josie E., Asadzadeh, Mohammad, Kelly, Steven L., Meis, Jacques F., Khan, Ziauddin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355561/
https://ncbi.nlm.nih.gov/pubmed/30455247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01900-18
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