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Immuno-engineered organoids for regulating the kinetics of B-cell development and antibody production
Induction of B-cell immunity against infection depends on the initiation of the germinal center (GC) reaction in secondary lymphoid organs. Ex vivo recapitulation of the GC reaction in 2D cultures results in transient cell growth, with poor yield and short-term survival. Furthermore, no reported 2D...
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| Publicado no: | Nat Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355337/ https://ncbi.nlm.nih.gov/pubmed/28005068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.157 |
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