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Detect differentially methylated regions using non-homogeneous hidden Markov model for methylation array data

MOTIVATION: DNA methylation is an important epigenetic mechanism in gene regulation and the detection of differentially methylated regions (DMRs) is enthralling for many disease studies. There are several aspects that we can improve over existing DMR detection methods: (i) methylation statuses of ne...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Shen, Linghao, Zhu, Jun, Robert Li, Shuo-Yen, Fan, Xiaodan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355111/
https://ncbi.nlm.nih.gov/pubmed/29036320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx467
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