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Transient p53 inhibition sensitizes aged white adipose tissue for beige adipocyte recruitment by blocking mitophagy

Aging of white adipose tissue (WAT) is associated with reduced insulin sensitivity, which contributes to whole-body glucose intolerance. WAT aging in mice impairs cold-induced beige adipocyte recruitment (beiging), which has been attributed to the senescence of adipose progenitor cells. Tumor suppre...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:FASEB J
Main Authors: Fu, Wenyan, Liu, Yang, Sun, Christina, Yin, Hang
פורמט: Artigo
שפה:Inglês
יצא לאור: Federation of American Societies for Experimental Biology 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355076/
https://ncbi.nlm.nih.gov/pubmed/30052487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800577R
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