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Context dependent roles for RB-E2F transcriptional regulation in tumor suppression
RB-E2F transcriptional control plays a key role in regulating the timing of cell cycle progression from G1 to S-phase in response to growth factor stimulation. Despite this role, it is genetically dispensable for cell cycle exit in primary fibroblasts in response to growth arrest signals. Mice engin...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6354955/ https://ncbi.nlm.nih.gov/pubmed/30703085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203577 |
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