Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility

Cell motility is essential for viral dissemination1. Vaccinia virus (VACV), a close relative of smallpox virus, is thought to exploit cell motility as a means to enhance the spread of infection1. A single viral protein, F11L, contributes to this by blocking RhoA signalling to facilitate cell retract...

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Vydáno v:Nat Microbiol
Hlavní autoři: Beerli, Corina, Yakimovich, Artur, Kilcher, Samuel, Reynoso, Glennys V., Fläschner, Gotthold, Müller, Daniel J., Hickman, Heather D., Mercer, Jason
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354922/
https://ncbi.nlm.nih.gov/pubmed/30420785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0288-2
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